侯庆华,宋文东,王浩,纪丽丽

• 1:广东海洋大学海洋药物研究室
• 2:广东海洋大学科研处
• 3:广东海洋大学食品科技学院

摘要(Abstract)：

从沿海藻类昆布(Thallus laminariae)中提取昆布多糖,经降解后得昆布寡糖。采用高脂饲料加小剂量链脲佐菌素法诱导SD大鼠2型糖尿病动物模型,成模后大鼠分为正常对照组,阴性对照组,二甲双胍组,昆布寡糖高、中、低剂量组,灌胃给予寡糖溶液8周,定期观察体重并采集血液标本进行检测。结果表明,昆布寡糖对糖尿病大鼠有明显的降低血糖,升高胰岛素,增加体重,降低甘油三酯、总胆固醇、游离脂肪酸,升高高密度脂蛋白胆固醇的作用,但对低密度脂蛋白胆固醇的影响不明显。可见,昆布寡糖对2型糖尿病大鼠具有明显治疗作用。

关键词(KeyWords)： 昆布寡糖;2型糖尿病;血糖

Abstract:

Keywords:

基金项目(Foundation): 广东省科技局项目(0609084)“海洋巨藻活性寡糖提取及天然降糖制剂的研究”

作者(Author): 侯庆华,宋文东,王浩,纪丽丽

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