彭勤,黄和

• 1:广东海洋大学食品科技学院广东省水产品加工与安全重点实验室广东普通高等学校水产品深加工重点实验室

摘要(Abstract)：

渔用麻醉剂的使用对减少水产品运输过程中的损失相比传统加氧加冰有着更好的效果和更低的成本,其中丁香酚类药物对鱼类的麻醉作用明显,是主流的渔用麻醉剂之一,但丁香酚类化合物对人体具有一定的伤害性。从样品前处理技术和水产品中丁香酚类麻醉剂残留检测技术两方面进行阐述,分析各种检测技术的优点和缺点,并展望了丁香酚类麻醉剂的检测技术的发展趋势。

关键词(KeyWords)： 水产品;丁香酚类麻醉剂;检测技术

Abstract:

Keywords:

基金项目(Foundation): 广东省科技计划项目(2014A020208121)

作者(Author): 彭勤,黄和

参考文献(References)：

• [1]苏明明,孙兴权,杨春光,等.渔用麻醉剂MS-222、丁香酚在鲜活水产品运输中的应用及检测方法研究进展[J].食品安全质量检测学报,2015,6(1):25-29.
• [2]杨州.水产动物活体运输方法[J].水产养殖,2002(1):38-39.
• [3]THOMPSON D C,BARHOUMI R,BURGHARDT R C.Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays[J].Toxicology and Applied Pharmacology,1998,149(1):5563.
• [4]GEORGE J D,PRICE C J,MARR M C,et al.Evaluation of the developmental toxicity of isoeugenol in Sprague-Dawley(CD)rats[J].Toxicological Sciences,2001,60(1):112-120.
• [5]U.S.Department of Health and Human Services Food and Drug Administration Center for Veterinary Medicine.Guidance for industry concerns related to the use of clove oil as an anesthetic for fish[EB/OL].(200704-24)[2017-08-15].http://www.fda.gov/downloads/Animal Veterinary/Guidance Compliance Enforcement/Guidancefo r Industry/ucm052520.pdf
• [6]LIAW S S,HABER PEREZ V H,ZHOU S,et al.Py-GC/MS studies and principal component analysis to evaluate the impact of feedstock and temperature on the distribution of products during fast pyrolysis[J].Journal of Analytical and Applied Pyrolysis,2014,109:140-151.
• [7]日本农林水产省水产厅和消费安全局.水産用医薬品の使用について[EB/OL].(2010-03-01)[2017-08-15].http://www.maff.go.jp/j/syouan/suisan/suisan_yobo/pdf/100316_suisan_iyakuhin.pdf.
• [8]李清.日本重新调整水产养殖用药规定[J].世界农业,2007(4):45-50.
• [9]DANIEL P.Available chemotherapy in Mediterranean fish farming:use and needs[M/OL].//ROGERS C,BASURCO B.The use of veterinary drugs and vaccines in Mediterranean aquaculture.Zaragoza:CIHEAM,2009(200901-01)[2017-08-15].http://ressources.ciheam.org/om/pdf/a86/00801072.pdf.
• [10]陈焕,黄和,高平,等.分散固相萃取-气相色谱法同时测定水产品中六种丁香酚类麻醉剂的残留量[J].食品工业科技,2015,36(8):88-92.
• [11]高平,黄和,刘文侠,等.固相萃取-高效液相色谱-荧光检测法测定水产品中4种丁香酚类化合物[J].中国食品卫生杂志,2016,28(1):56-61.
• [12]柯常亮,刘奇,陈洁文,等.气相色谱-串联质谱联用法测定水中丁香酚残留[J].中国渔业质量与标准,2014,4(4):49-55.
• [13]何洪健,黄和,高平,等.MISPE-HPLC检测水产品5种丁香酚麻醉剂的残留量[J].食品与机械,2016,32(11):39-44.
• [14]陈焕,黄和,高平,等.高效液相色谱法测定水产品中丁香酚类麻醉剂的残留量[J].食品与发酵工业,2014,40(12):156-160.
• [15]SARAN S,MENON S,SHAILAJAN S,et al.Validated RP-HPLC method to estimate eugenol from commercial formulations like Caturjata Churna,Lavangadi Vati,Jatiphaladi Churna,Sitopaladi Churna,and clove oil[J].Journal of Pharmacy Research,2013,6(1):53-60.
• [16]MEINERTZ J R,HESS K R.Evaluation of analytical techniques to determine AQUI-S?20E(eugenol)concentrations in water[J].Aquaculture,2014,418-419:62-66.
• [17]BILIA A R,FLAMINI G,TAGLIOLI V,et al.GC–MS analysis of essential oil of some commercial Fennel teas[J].Food Chemistry,2002,76(3):307-310.
• [18]YE L.Development and validation of a LC-MS/MS method for the determination of isoeugenol in finfish[J].Food Chemistry,2017,228:70-76.
• [19]LI Y H,SUN Z H,ZHENG P.Determination of Vanillin,Eugenol and Isoeugenol by RP-HPLC[J].Chromatographia,2004,60(11/12):709-713.
• [20]芦智远,刘辰乾,冯歆轶,等.超高效液相色谱-串联质谱法鱼肉丁香酚的残留量测定[J].科学养鱼,2016(7):76-77.
• [21]GURSALE A,DIGHE V,Parekh G.Simultaneous quantitative determination of cinnamaldehyde and methyl eugenol from stem bark of Cinnamomum zeylanicum Blume using RP-HPLC[J].Journal of chromatographic science,2010,48(1):59-62.
• [22]MEINERTZ J R,SCHREIER T M,PORCHER S T,et al.Depletion of eugenol residues from the skin-on fillet tissue of rainbow trout exposed to 14 C-labeled eugenol[J].Aquaculture,2014,430:74-78.
• [23]赵东豪,王强,王旭峰,等.超高效液相色谱-串联质谱法检测鱼肉和暂养水中丁香酚残留量[J].食品科学,2016,37(24):252-256.
• [24]LI J C,ZHANG J,LIU Y.Optimization of solid-phaseextraction cleanup and validation of quantitative determination of eugenol in fish samples by gas chromatography-tandem mass spectrometry[J].Analytical and Bioanalytical Chemistry,2015,407(21):6563-6568.
• [25]LI J C,LIU H,WANG C Y,et al.Determination of eugenol in fish and shrimp muscle tissue by stable isotope dilution assay and solid-phase extraction coupled gas chromatography-triple quadrupole mass spectrometry[J].Analytical&Bioanalytical Chemistry,2016,408(24):6537-6544.
• [26]刘海新,余颖,汤水粉,等.气相色谱质谱法测定养殖水体中丁香酚含量不确定度评定[J].渔业研究,2016,38(4):310-317.
• [27]SCHULZ K,SCHLENZ K,MALT S,et al.Headspace solid-phase microextraction-gas chromatography-mass spectrometry for the quantitative determination of the characteristic flavouring agent eugenol in serum samples after enzymatic cleavage to validate post-offence alcohol drinking claims[J].Journal of Chromatography A,2008,1211(1):113-119.
• [28]吴仕辉,朱新平,郑光明,等.高效液相色谱法检测水产品中的孔雀石绿和结晶紫[J].广东海洋大学学报,2009,29(01):54-57.
• [29]苏垒.气相色谱仪热导检测器的研究与设计[D].成都:西华大学,2012.
• [30]李兴洲.氢火焰离子化检测器的工作原理与特性[J].印刷技术,2012(2):45-46.
• [31]汤菊芬,王蓓,蔡佳,等.水产品中盐酸小檗碱的高效液相色谱-串联质谱法测定[J].广东海洋大学学报,2014,34(04):62-66.
• [32]方晓磊.青石斑鱼中丁香酚的残留消除特征研究[D].舟山:浙江海洋大学,2017.
• [33]KILDEA M A,ALLANB G L,KEARNE R E et al.Accumulation and clearance of the anaesthetics clove oil and AQUI-Sk from the edible tissue of silver perch(Bidyanus bidyanus).Aquaculture,2004,266:265-277.
• [34]余颖.气相色谱-质谱法测定鱼肉中丁香酚的残留[J].福州大学学报,2015,43(2):266-270.
• [35]陈焕.水产品中丁香酚类麻醉剂残留检测方法的研究[D].湛江:广东海洋大学,2015.