蔡吉榛,罗显桥,林红英,刘寒,马驿,巨向红,陈进军,陆长青,岳杰

• 1:广东海洋大学农学院

摘要(Abstract)：

为探究湛江近海域海洋沉积物中含氯多环芳烃的生物学毒性效应,选取湛江近海域2个地点(TS和JSW)采集样品,以含氯多环芳烃为目标,制备沉积物提取物,将斑马鱼胚胎胚胎暴露于不同浓度的沉积物提取物中,观测供试斑马鱼胚胎的死亡和畸形情况。结果表明:TS采样点沉积物提取物的LC50为15.98 mg/mL(48 h)和14.41mg/mL(96 h),JSW采样点沉积物提取物的LC50为19.89 mg/mL(48 h)和16.36 mg/mL(96 h),且致死效应呈现浓度依赖关系;TS和JSW 2个采样点沉积物中含氯多环芳烃能导致斑马鱼胚胎卵黄囊水肿、心包水肿、脊椎弯曲等致畸效应,其致畸效应与暴露浓度基本呈浓度依赖关系。湛江近海域沉积含氯多环芳烃物提取物对斑马鱼胚胎具有明显的致死作用和致畸毒性。

关键词(KeyWords)： 湛江近海域;含氯多环芳烃;半数致死浓度;致畸性;斑马鱼胚胎

Abstract:

Keywords:

基金项目(Foundation): 广东省科技计划国际合作项目(2007B050200023;2010B050600004)

作者(Author): 蔡吉榛,罗显桥,林红英,刘寒,马驿,巨向红,陈进军,陆长青,岳杰

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