朱国萍,章超桦,曹文红,卢虹玉,秦小明,高加龙,郑惠娜

• 1:广东海洋大学食品科技学院//国家贝类加工技术研发分中心(湛江)//广东省水产品加工与安全重点实验室//广东省海洋生物制品工程实验室//水产品深加工广东普通高等学校重点实验室

摘要(Abstract)：

【目的】探究牡蛎酶解产物改善小鼠学习记忆的功效作用及其营养成分组成。【方法】采用中性蛋白酶酶解牡蛎获得牡蛎酶解产物,测定其氨基酸及无机元素的含量;采用跳台实验、避暗实验和Morris水迷宫实验对喂食高(3.0 g/kg)、中(1.5 g/kg)、低剂量(0.75 g/kg)的牡蛎酶解产物及药物吡拉西坦(1.6 g/kg)30 d的正常小鼠进行行为学测定。【结果】牡蛎酶解产物无机元素含量丰富,谷氨酸占总氨基酸含量为15.7%,牛磺酸及锌质量分数分别为2.85 g/100g、175 mg/100g。高剂量牡蛎酶解产物能延长跳台消退实验小鼠的潜伏期;高、中、低三剂量牡蛎酶解产物均能降低避暗消退实验错误动物数,且高剂量牡蛎酶解产物能显著延长避暗消退实验小鼠的潜伏期(P <0.05);高、中、低三剂量牡蛎酶解产物能显著缩短定位航行实验小鼠上台前的路程及潜伏期(P <0.05),且高剂量牡蛎酶解产物能显著提高空间探索实验小鼠穿越平台的次数(P<0.05)。【结论】牡蛎酶解产物具有提高小鼠学习记忆能力的功效作用。

关键词(KeyWords)： 牡蛎酶解产物;学习记忆;行为测试;营养成分

Abstract:

Keywords:

基金项目(Foundation): 贝类产业技术体系（CARS-49）;; 广东普通高等学校水产品高值化加工与利用创新团队项目（GDOU2016030503）;; 海洋贝类营养健康食品关键技术及产业化（GDOU2017052606）

作者(Author): 朱国萍,章超桦,曹文红,卢虹玉,秦小明,高加龙,郑惠娜

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